When the complement system is activated, target cells will be lysed and phagocytosis will be encouraged by opsonization. Quantification of the individual complement elements is possible, but this does not reveal anything about the pathway's activity. Total complement activity/CH 50, commonly referred to as CH 100, is a screening test for the classical complement pathway's activation. Any component in the pathway that is reduced, deleted, or inactivated will affect it. In order to more accurately ascertain the occurrence, severity, and response to treatment, the total complement activity test can thoroughly comprehend the complement system's activation status. The complement activity test therefore has a huge clinical impact on illness diagnosis and subsequent treatment.
